Geometry Daily
Reposted via Sara Raines
Wednesday, March 30, 2016
I Love someone so mu
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Reposted via Jessica Shires
I Love someone so much YOU take them in your arms & kiss them really hard & passionately!!!
Reposted via Jessica Shires
Soyoo Joyful Growth Center / Crossboundaries
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Reposted via ArchDaily
Since 2002, the overpopulated city of Zhengzhou has been developing its new financial center, Zhengdong New Area, within China’s Central Plains Economic Region. The area, once dubbed by international media as one of China’s largest “ghost districts”, is where Crossboundaries’ latest completed project - Soyoo Joyful Growth Center, is situated. The building is part of a triumvirate of desolate round buildings, never used since it was built as a business center 10 years ago.
Reposted via ArchDaily
silver-milleniun: By mIzcoma●ミズコマ(via Tumbling)
http://ift.tt/1NGZLyZ
Reposted via Ashe Maree ♡ nsfw Not♡safe♡for♡jerks
By mIzcoma●ミズコマ(via Tumbling)
Reposted via Ashe Maree ♡ nsfw Not♡safe♡for♡jerks
Tuesday, March 29, 2016
Corps: Twice since 2015, Congress has declined to fund work on Dallas Floodway project
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The history of the Trinity River in one map courtesy the U.S. Army Corps of Engineers In April 2014, the Army Corps of Engineers told the City Council that the Dallas Floodway — otherwise known as the Trinity River levees … Continue reading →
Reposted via City Hall Blog
The history of the Trinity River in one map courtesy the U.S. Army Corps of Engineers In April 2014, the Army Corps of Engineers told the City Council that the Dallas Floodway — otherwise known as the Trinity River levees … Continue reading →
Reposted via City Hall Blog
Learn How to Identify Human Proteins and Contribute to Science in EVE #CitizenScience
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If you are a gamer and a lover of biology, you are going to go crazy over Project Discovery, a new addition to the EVE game which promotes citizen science, according to International Business Times. This is an inventive collaboration between CCP Games, Human Protein Atlas, Massively Multiplayer Online Science, and Reykjavik University students. It […]
Reposted via Adafruit Industries – Makers, hackers, artists, designers and engineers!
If you are a gamer and a lover of biology, you are going to go crazy over Project Discovery, a new addition to the EVE game which promotes citizen science, according to International Business Times. This is an inventive collaboration between CCP Games, Human Protein Atlas, Massively Multiplayer Online Science, and Reykjavik University students. It […]
Reposted via Adafruit Industries – Makers, hackers, artists, designers and engineers!
Territory Without Ground: Designing in the Sahara Desert
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Reposted via ArchDaily
The Pavilion of Morocco at the 14th Venice Biennale, Fundamentals, focused on territorial speculations in the Sahara: Inhabiting the Uninhabitable. For the exhibition, which was the country's first representation at the Biennale, Paris-based practice OUALALOU+CHOI proposed an urban structure for this desert territory – "a means of putting down roots, implanting urbanity and civilization. The Sahara, with its extreme geography and climatic conditions, remains unexplored territory for architectural speculation."
Reposted via ArchDaily
Wilonsky: Mayor promises this Trinity River park concept will be the greatest of all park concepts
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Nope. Not gonna happen. This is how long Dallas has wrestled with trying to plant a park next to the Trinity River. Ebby Halliday, the beloved Dallas real estate icon, was born in 1911, the year George Kessler presented “A … Continue reading →
Reposted via City Hall Blog
Nope. Not gonna happen. This is how long Dallas has wrestled with trying to plant a park next to the Trinity River. Ebby Halliday, the beloved Dallas real estate icon, was born in 1911, the year George Kessler presented “A … Continue reading →
Reposted via City Hall Blog
phantomas47: A smile is the prettiest thing you can wear. : )...
http://ift.tt/1iRSeAO
Reposted via F&O Fabforgottennobility
A smile is the prettiest thing you can wear.
: ) ♡
Reposted via F&O Fabforgottennobility
Monday, March 28, 2016
Biological mechanism passes on long-term epigenetic 'memories' from parents to children
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According to epigenetics -- the study of inheritable changes in gene expression not directly coded in our DNA -- our life experiences may be passed on to our children and our children's children. Studies on survivors of traumatic events have suggested that exposure to stress may indeed have lasting effects on subsequent generations. But how exactly are these genetic "memories" passed on?
A new Tel Aviv University study pinpoints the precise mechanism that turns the inheritance of environmental influences "on" and "off." The research, published last week in Cell and led by Dr. Oded Rechavi and his group from TAU's Faculty of Life Sciences and Sagol School of Neuroscience, reveals the rules that dictate which epigenetic responses will be inherited, and for how long.
"Until now, it has been assumed that a passive dilution or decay governs the inheritance of epigenetic responses," Dr. Rechavi said. "But we showed that there is an active process that regulates epigenetic inheritance down through generations."
Highlights
•New RNAi episodes extend the duration of heritable epigenetic effects
•Amplification of heritable exo-siRNAs occurs at the expense of endo-siRNAs
•A feedback between siRNAs and RNAi genes determines heritable silencing duration
•Modified transgenerational epigenetic kinetics (MOTEK) mutants are identified
Summary
In C. elegans, small RNAs enable transmission of epigenetic responses across multiple generations. While RNAi inheritance mechanisms that enable “memorization” of ancestral responses are being elucidated, the mechanisms that determine the duration of inherited silencing and the ability to forget the inherited epigenetic effects are not known. We now show that exposure to dsRNA activates a feedback loop whereby gene-specific RNAi responses dictate the transgenerational duration of RNAi responses mounted against unrelated genes, elicited separately in previous generations. RNA-sequencing analysis reveals that, aside from silencing of genes with complementary sequences, dsRNA-induced RNAi affects the production of heritable endogenous small RNAs, which regulate the expression of RNAi factors. Manipulating genes in this feedback pathway changes the duration of heritable silencing. Such active control of transgenerational effects could be adaptive, since ancestral responses would be detrimental if the environments of the progeny and the ancestors were different.
Passing stress from one generation to the next
Researchers have been preoccupied with how the effects of stress, trauma, and other environmental exposures are passed from one generation to the next for years. Small RNA molecules -- short sequences of RNA that regulate the expression of genes -- are among the key factors involved in mediating this kind of inheritance. Dr. Rechavi and his team had previously identified a "small RNA inheritance" mechanism through which RNA molecules produced a response to the needs of specific cells and how they were regulated between generations.
Cell - A Tunable Mechanism Determines the Duration of the Transgenerational Small RNA Inheritance in C. elegans
Read more »
Reposted via Next Big Future
According to epigenetics -- the study of inheritable changes in gene expression not directly coded in our DNA -- our life experiences may be passed on to our children and our children's children. Studies on survivors of traumatic events have suggested that exposure to stress may indeed have lasting effects on subsequent generations. But how exactly are these genetic "memories" passed on?
A new Tel Aviv University study pinpoints the precise mechanism that turns the inheritance of environmental influences "on" and "off." The research, published last week in Cell and led by Dr. Oded Rechavi and his group from TAU's Faculty of Life Sciences and Sagol School of Neuroscience, reveals the rules that dictate which epigenetic responses will be inherited, and for how long.
"Until now, it has been assumed that a passive dilution or decay governs the inheritance of epigenetic responses," Dr. Rechavi said. "But we showed that there is an active process that regulates epigenetic inheritance down through generations."
Highlights
•New RNAi episodes extend the duration of heritable epigenetic effects
•Amplification of heritable exo-siRNAs occurs at the expense of endo-siRNAs
•A feedback between siRNAs and RNAi genes determines heritable silencing duration
•Modified transgenerational epigenetic kinetics (MOTEK) mutants are identified
Summary
In C. elegans, small RNAs enable transmission of epigenetic responses across multiple generations. While RNAi inheritance mechanisms that enable “memorization” of ancestral responses are being elucidated, the mechanisms that determine the duration of inherited silencing and the ability to forget the inherited epigenetic effects are not known. We now show that exposure to dsRNA activates a feedback loop whereby gene-specific RNAi responses dictate the transgenerational duration of RNAi responses mounted against unrelated genes, elicited separately in previous generations. RNA-sequencing analysis reveals that, aside from silencing of genes with complementary sequences, dsRNA-induced RNAi affects the production of heritable endogenous small RNAs, which regulate the expression of RNAi factors. Manipulating genes in this feedback pathway changes the duration of heritable silencing. Such active control of transgenerational effects could be adaptive, since ancestral responses would be detrimental if the environments of the progeny and the ancestors were different.
Passing stress from one generation to the next
Researchers have been preoccupied with how the effects of stress, trauma, and other environmental exposures are passed from one generation to the next for years. Small RNA molecules -- short sequences of RNA that regulate the expression of genes -- are among the key factors involved in mediating this kind of inheritance. Dr. Rechavi and his team had previously identified a "small RNA inheritance" mechanism through which RNA molecules produced a response to the needs of specific cells and how they were regulated between generations.
Cell - A Tunable Mechanism Determines the Duration of the Transgenerational Small RNA Inheritance in C. elegans
Read more »
Reposted via Next Big Future
Saturday, March 26, 2016
First fully autonomous drone delivery to an urban residence in the USA
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Drone delivery company, Flirtey, has made the first urban delivery in the United States by a fully autonomous drone.
Flirtey started in 2013 in Australia, delivering textbooks to universities, before it moved to Nevada. Its six-engine multicopter flew along a predetermined path. When it reached the target house, it lowered a package containing bottled water, emergency food, and a first aid kit. The house was uninhabited, as the flight was a demonstration of what a rescue drone might be able to carry to people in need. Flirtey already conducted a rural delivery test, so it makes sense that urban was next, even if that “urban” is defined as a fairly small town. According to Flirtey CEO Matthew Sweeney, 86% of packages are 5.5 pounds or less, and that the drone is designed to carry payloads that size up to 10 miles away.
UAVs can be operated commercially in a growing number of countries. Flirtey is in discussions with regulators all around the world, and in particular, Flirtey is pioneering drone delivery in New Zealand.
In July 2015, Australian commercial drone startup Flirtey recently made the first ever drone parcel delivery in Auckland, New Zealand by transporting auto parts 2km. Partnering with Fastway Couriers, Flirtey’s drone was able to make the 20-minute car trip in under five minutes.
Read more » 
Reposted via Next Big Future
Drone delivery company, Flirtey, has made the first urban delivery in the United States by a fully autonomous drone.
Flirtey started in 2013 in Australia, delivering textbooks to universities, before it moved to Nevada. Its six-engine multicopter flew along a predetermined path. When it reached the target house, it lowered a package containing bottled water, emergency food, and a first aid kit. The house was uninhabited, as the flight was a demonstration of what a rescue drone might be able to carry to people in need. Flirtey already conducted a rural delivery test, so it makes sense that urban was next, even if that “urban” is defined as a fairly small town. According to Flirtey CEO Matthew Sweeney, 86% of packages are 5.5 pounds or less, and that the drone is designed to carry payloads that size up to 10 miles away.
UAVs can be operated commercially in a growing number of countries. Flirtey is in discussions with regulators all around the world, and in particular, Flirtey is pioneering drone delivery in New Zealand.
In July 2015, Australian commercial drone startup Flirtey recently made the first ever drone parcel delivery in Auckland, New Zealand by transporting auto parts 2km. Partnering with Fastway Couriers, Flirtey’s drone was able to make the 20-minute car trip in under five minutes.
Today, we're thrilled to announce @Fly_Flirtey successfully completed the first fully autonomous FAA-approved urban drone delivery in the US— Flirtey (@Fly_Flirtey) March 25, 2016
Read more »
Reposted via Next Big Future
DARPA wants machine learning embedded into devices to collaboratively share wireless spectrum
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The $2 million DARPA Spectrum Collaboration Challenge (SC2) is about getting the billions to trillions of wireless devices to efficiently share the wireless spectrum.
Teams will be rewarded for developing smart systems that collaboratively, rather than competitively, adapt in real time to today’s fast-changing, congested spectrum environment—redefining the conventional spectrum management roles of humans and machines in order to maximize the flow of radio frequency (RF) signals. DARPA officials unveiled the new Challenge before some 8000 engineers and communications professionals gathered in Las Vegas at the International Wireless Communications Expo (IWCE).
The primary goal of SC2 is to imbue radios with advanced machine-learning capabilities so they can collectively develop strategies that optimize use of the wireless spectrum in ways not possible with today’s intrinsically inefficient approach of pre-allocating exclusive access to designated frequencies. The challenge is expected to both take advantage of recent significant progress in the fields of artificial intelligence and machine learning and also spur new developments in those research domains, with potential applications in other fields where collaborative decision-making is critical.
“DARPA Challenges have traditionally rewarded teams that dominate their competitors, but when it comes to making the most of the electromagnetic spectrum, the team that shares most intelligently is going to win,” said SC2 program manager Paul Tilghman of DARPA’s Microsystems Technology Office (MTO). “We want to radically accelerate the development of machine-learning technologies and strategies that will allow on-the-fly sharing of spectrum at machine timescales.”
Read more » 
Reposted via Next Big Future
The $2 million DARPA Spectrum Collaboration Challenge (SC2) is about getting the billions to trillions of wireless devices to efficiently share the wireless spectrum.
Teams will be rewarded for developing smart systems that collaboratively, rather than competitively, adapt in real time to today’s fast-changing, congested spectrum environment—redefining the conventional spectrum management roles of humans and machines in order to maximize the flow of radio frequency (RF) signals. DARPA officials unveiled the new Challenge before some 8000 engineers and communications professionals gathered in Las Vegas at the International Wireless Communications Expo (IWCE).
The primary goal of SC2 is to imbue radios with advanced machine-learning capabilities so they can collectively develop strategies that optimize use of the wireless spectrum in ways not possible with today’s intrinsically inefficient approach of pre-allocating exclusive access to designated frequencies. The challenge is expected to both take advantage of recent significant progress in the fields of artificial intelligence and machine learning and also spur new developments in those research domains, with potential applications in other fields where collaborative decision-making is critical.
“DARPA Challenges have traditionally rewarded teams that dominate their competitors, but when it comes to making the most of the electromagnetic spectrum, the team that shares most intelligently is going to win,” said SC2 program manager Paul Tilghman of DARPA’s Microsystems Technology Office (MTO). “We want to radically accelerate the development of machine-learning technologies and strategies that will allow on-the-fly sharing of spectrum at machine timescales.”
Read more »
Reposted via Next Big Future
Olson Kundig Take Home Top Honors in 2016 Fairy Tales Competition
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Reposted via ArchDaily
Blank Space has announced three winners and ten honorable mentions in their third Fairy Tales Competition. This year's contest drew entries from more than 1,500 participants from 67 countries. Everyone from students to academics and notable studios and designers submitted detailed stories and beautiful visuals for their submissions. The winners were chosen by an interdisciplinary jury of distinguished judges including Hans-Ulrich Obrist, Co-Director of the Serpentine Galleries; Elizabeth Diller, founding partner at Diller Scofidio + Renfro, and ArchDaily’s own Becky Quintal, Executive Editor; and David Basulto, Founder and Editor in Chief.
Reposted via ArchDaily
BIG_CLOCK Made From Six 3″ 7-Segment LCDs
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Pierre Muth is a fan of clocks. Then again who shouldn’t be? We all look at them dozens – if not hundreds – of times each day. And he had some spare 7-segment LCDs laying around, so he built a clock! We need clocks. Once you have passionate activities which absorbs all your attention, if […]
Reposted via Adafruit Industries – Makers, hackers, artists, designers and engineers!
Pierre Muth is a fan of clocks. Then again who shouldn’t be? We all look at them dozens – if not hundreds – of times each day. And he had some spare 7-segment LCDs laying around, so he built a clock! We need clocks. Once you have passionate activities which absorbs all your attention, if […]
Reposted via Adafruit Industries – Makers, hackers, artists, designers and engineers!
Inside a Counterfeit MagSafe Charger #teardown
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I especially love the metal ground pin … umm, “connection” (and other external fake features) along with the ‘just put this here’ heatsink approach. Wow! From the outside, this charger is almost a perfect match for an Apple charger, but disassembling the charger shows that it is very different on the inside. It has a […]
Reposted via Adafruit Industries – Makers, hackers, artists, designers and engineers!
I especially love the metal ground pin … umm, “connection” (and other external fake features) along with the ‘just put this here’ heatsink approach. Wow! From the outside, this charger is almost a perfect match for an Apple charger, but disassembling the charger shows that it is very different on the inside. It has a […]
Reposted via Adafruit Industries – Makers, hackers, artists, designers and engineers!
US Army wants nano drone to support soldiers 500 meter awareness and targeting assistance in urban and other settings
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Army leaders want to build a nano drone that weighs less than a pound with the entire unmanned system not weighing more than three pounds, according to a Request for Information released on FBO.gov on March 1.
The Army is calling its nano drone efforts, the Soldier Borne Sensors (SBS) program with Product Manager Soldier Maneuver Sensors (PM SMS) leading the work to outfit soldiers with these high tech unmanned systems.
Developing nano drones to fly through buildings to protect soldiers before having to clear rooms is a high priority for Army leaders. The technology is catching up to Army expectations.
The British Army deploy the Black Hornet nano drone (pictured above) to Afghanistan in 2013. Built by Prox Dynamics, the nano drone measures 4 inches long and weighs only 16 grams to include batteries. It carries three cameras and can fly up to 11 mph.
The PD-100 Personal Reconnaisance System (PRS) made by the Norwegian company Prox Dynamics provides the modern day warrior with a game-changing piece of equipment for instant use on the battlefield. (Image courtesy Prox Dynamics)
US Army wants a bigger drone with more range and better cameras than the PD-100
Read more » 
Reposted via Next Big Future
Army leaders want to build a nano drone that weighs less than a pound with the entire unmanned system not weighing more than three pounds, according to a Request for Information released on FBO.gov on March 1.
The Army is calling its nano drone efforts, the Soldier Borne Sensors (SBS) program with Product Manager Soldier Maneuver Sensors (PM SMS) leading the work to outfit soldiers with these high tech unmanned systems.
Developing nano drones to fly through buildings to protect soldiers before having to clear rooms is a high priority for Army leaders. The technology is catching up to Army expectations.
The British Army deploy the Black Hornet nano drone (pictured above) to Afghanistan in 2013. Built by Prox Dynamics, the nano drone measures 4 inches long and weighs only 16 grams to include batteries. It carries three cameras and can fly up to 11 mph.
US Army wants a bigger drone with more range and better cameras than the PD-100
- The display will be visible in day or night and backlit with brightness and contrast controls.
- The system will accept a standard interoperable charging configuration with Military Standard and widely commercially available chargers.
- Air vehicle must operate in manual mode and operate in waypoint navigation mode.
- Air vehicle’s operating radius: Line of Sight: 500 meters
- Air vehicle’s mission endurance: 15 mins
- Air vehicle shall have, at range of 100 meters day (50 meters night), sufficient resolution for a trained operator to detect a man-sized target with a 90% probability.
- Air vehicle shall have, at range of 20 meters during the day, sufficient resolution for a trained operator to recognize a man-sized target and determine if armed with a rifle or not with a 90% probability.
- Air vehicle will have the ability to be hand launched and recovered, without exposing the operator, while in the prone position and while from cover & concealment, a hide site, confined area and alleyway type locations.
- Air vehicle’s launch time from stored to operational is less than 60 seconds.
- Air vehicle must be operable in constant winds up to 10 knots and gusts to 15 knots.
Read more »
Reposted via Next Big Future
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