Thursday, September 25, 2014

New Cas9 mouse model will be easier to CRISPR gene-edit and enable faster progress against diseases like cancer

http://ift.tt/hZ0OVi

Researchers from the Broad Institute and MIT have created a new mouse model to simplify application of the CRISPR-Cas9 system for genome-editing experiments in living animals.



The researchers successfully used the new “Cas9 mouse” model to edit multiple genes in a variety of cell types, and to model lung adenocarcinoma, one of the most lethal human cancers. The mouse has already been made available to the scientific community and is being used by researchers at more than a dozen institutions.








Journal Cell - CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling



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Reposted via Next Big Future

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