Saturday, November 28, 2015

Overview of regenerative dentistry and stem cells for dental applications

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Teeth are the most natural, noninvasive source of stem cells. Dental stem cells, which are easy, convenient, and affordable to collect, hold promise for a range of very potential therapeutic applications. We have reviewed the ever-growing literature on dental stem cells archived in Medline using the following key words: Regenerative dentistry, dental stem cells, dental stem cells banking, and stem cells from human exfoliated deciduous teeth. Relevant articles covering topics related to dental stem cells were shortlisted and the facts are compiled. The objective of this review article is to discuss the history of stem cells, different stem cells relevant for dentistry, their isolation approaches, collection, and preservation of dental stem cells along with the current status of dental and medical applications.

Regenerative capacity of the dental pulp is well-known and has been recently attributed to function of dental stem cells. Dental stem cells offer a very promising therapeutic approach to restore structural defects and this concept is extensively explored by several researchers, which is evident by the rapidly growing literature in this field. For this review article a literature research covering topics related to dental stem cells was made and the facts are compiled.

Human dental stem cells that have been isolated and characterized are:

  • DPSCs.(Dental pulp stem cells)
  • SHED.(Stem cells from human exfoliated deciduous teeth)
  • Stem cells from apical papilla (SCAP).
  • Periodontal ligament stem cells (PDLSCs).


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Reposted via Next Big Future

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